[Clinical study and effect of nitroxoline on fecal flora in children].

Authors:
  • NLN Lambert-Zechovsky
    N Lambert-Zechovsky
  • BLB Lévêque
    B Lévêque
  • EBE Bingen
    E Bingen
  • GPG Pillion
    G Pillion
  • JCJ Chapelle
    J Chapelle
  • HMH Mathieu
    H Mathieu
Google Scholar
  • 1 May 1987
    • journal article
    • abstracts
    • Vol. 35  (5) , 669-72
    • PMID:3302880
Abstract
Twelve children (mean age: 4) are treated in practice office with nitroxoline (200 mg/kg/24 h) during 10 days for urinary tract infection. A study on the effect of nitroxoline against the fecal flora is undertaken in a group of 21 children who receive nitroxoline during 4 days or a long period. Bacteriological and clinical efficacy is checked when urinary concentrations of nitroxoline are greater than 16 mg/l. The results show 8 clinical and bacteriological success one true failure and 3 failure due to a non-compliance to the treatment. No qualitative and quantitative modification of the fecal flora is observed after treatment with nitroxoline.