Smoldering Acute Leukemia

Authors:
  • JRJack J. Rheingold
    Jack J. Rheingold
  • RKRichard Kaufman
    Richard Kaufman
  • EAEdward Adelson
    Edward Adelson
  • ALArnold Lear
    Arnold Lear

Abstract
WE have recently seen a number of patients with acute leukemia of an atypical variety that has received little attention in the literature. These cases smolder along with low-grade clinical intensity for a period of months to years. They may continue in this fashion until death occurs from infection or other complications, or they may burst forth into a more typical picture of acute leukemia. During the smoldering phase the diagnosis may be obvious or occult. Even in the latter group, however, the diagnosis can be made if one is alert to this entity.The following cases are representative of . . .
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