Sleep and Immune Function
Open Access
- 1 April 2012
- journal article
- review article
- Published by AACN Publishing in Critical Care Nurse
- Vol. 32 (2) , e19-e25
Abstract
Scientists are only beginning to fully understand the purpose of sleep and its underlying mechanisms. Lack of sleep is associated with many diseases, including infection, and with increased mortality. Lack of proper sleep is an important problem in the intensive care unit, and interventions have been designed to improve it. Sleep is associated with immune function, and this relationship is partially based on the physiological basis of sleep, sleep architecture, the sleep-wake cycle, cytokines and the hypothalamic-pituitary axis.Keywords
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