Evidence of a Major Reservoir of Non-Malarial Febrile Diseases in Malaria-Endemic Regions of Bangladesh
Authors:
- Harald NoedlHNHarald Noedl
- Julia MattJMJulia Matt
- Rashidul HaqueRHRashidul Haque
- Hans-Peter FuehrerHans-Peter Fuehrer
- Wasif A. KhanWKWasif A. Khan
- Peter StarzengruberPSPeter Starzengruber
- Milena K. S. MuellerMMMilena K. S. Mueller
- Johannes A. B. ReismannJRJohannes A. B. Reismann
- Mariella JungMJMariella Jung
- Benedikt LeyBenedikt Ley
- Markus A. FallyMFMarkus A. Fally
- 5 February 2014
- journal article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 90 (2) , 377-382
Abstract
In malaria-endemic regions any febrile case is likely to be classified as malaria based on presumptive diagnosis largely caused by a lack of diagnostic resources. A district-wide prevalence study assessing etiologies of fever in 659 patients recruited in rural and semi-urban areas of Bandarban district in southeastern Bangladesh revealed high proportions of seropositivity for selected infectious diseases (leptospirosis, typhoid fever) potentially being misdiagnosed as malaria because of similarities in the clinical presentation. In an area with point prevalences of more than 40% for malaria among fever cases, even higher seroprevalence rates of leptospirosis and typhoid fever provide evidence of a major persistent reservoir of these pathogens.Keywords
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