Dopaminergic genetic variation moderates the effect of nicotine on cigarette reward
- 26 October 2015
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 233 (2) , 351-360
Abstract
Cigarette smoking is influenced by nicotine’s effects on dopaminergic activity in the mesocorticolimbic pathway. This activity appears to be moderated by genetic variation, specifically a variable number tandem repeat (VNTR) polymorphism in the third exon of the dopamine receptor gene (DRD4).Keywords
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