Chemical constituents from the Saposhnikovia divaricata and their antiproliferative activity

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Abstract
Nine compounds were isolated and identified from ethanolic extracts of Saposhnikovia divaricata, including one new alkaloid (1), one new pentacyclic triterpenoid (9), and seven known alkaloids (2–8). Structural elucidation of compounds 1 and 9 was established by 1D and 2D NMR spectra referring to the literature, together with high-resolution mass spectrometric analysis. All compounds were evaluated for antiproliferative activity against two cancer cell lines (LN229, A549) in vitro. Compounds (1–9) showed no significant antiproliferative activity.
Funding Information
  • Science and Technology Innovation Project for College Students (2023yjscx001)
  • Heilongjiang Province “Double First Class” Discipline Collaborative Innovation Achievement Construction Project (LJGXCG2022-096)
  • National Natural Science Foundation of China (U22A20370)
  • Key Research and Development Plan of Heilongjiang Province (GA21D008)
  • Heilongjiang Touyan Innovation Team Program ([2019]5)
  • National Natural Science Foundation of China (Unassigned)

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