Salinity and prolactin regulate anoctamin 1 in the model teleost, Fundulus heteroclitus
- 1 November 2024
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Vol. 327 (5) , R479-R485
Abstract
In this study, we provide evidence in a teleost fish that the Ca2+-activated Cl− channel, anoctamin 1 may provide an additional path for Cl− secretion by seawater-type ionocytes. Not only is this the first report of a Cftr-independent Cl−-secreting pathway conferring survival in seawater but also the first description of its regulation by the pituitary hormone prolactin.Keywords
Funding Information
- National Science Foundation (IOS-1755131)
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