Adaptive autophagy in Alexander disease-affected astrocytes

Authors:
  • GTGuomei Tang
    Guomei Tang
  • ZYZhenyu Yue
    Zhenyu Yue
  • ZTZsolt Tallóczy
    Zsolt Tallóczy
  • JGJames E. Goldman
    James E. Goldman
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Abstract
The ubiquitin-proteasome and autophagy-lysosomal pathways are the two main routes of protein and organelle clearance in eukaryotic cells. The proteasome system is responsible for unfolded, short-li...