Promoter methylation and downregulation of SLC22A18 are associated with the development and progression of human glioma
Open Access
- 21 September 2011
- journal article
- Published by Springer Nature in Journal of Translational Medicine
- Vol. 9 (1) , 156
Abstract
Downregulation of the putative tumor suppressor gene SLC22A18 has been reported in a number of human cancers. The aim of this study was to investigate the relationship between SLC22A18 downregulation, promoter methylation and the development and progression of human glioma.Keywords
This publication has 25 references indexed in Scilit:
- Mosaic Analysis with Double Markers Reveals Tumor Cell of Origin in GliomaCell, 2011
- Selective inhibition of PDGFR by imatinib elicits the sustained activation of ERK and downstream receptor signaling in malignant glioma cellsInternational Journal of Oncology, 2011
- Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1Development, 2010
- Characterization of the human SLC22A18 gene promoter and its regulation by the transcription factor Sp1Gene, 2009
- p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiationNature, 2008
- Inhibitory effect of dimeric β peptide on the recurrence and metastasis of hepatocellular carcinoma in vitro and in miceWorld Journal of Gastroenterology, 2008
- Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasionLaboratory Investigation, 2006
- Gain of imprinting of SLC22A18 sense and antisense transcripts in human breast cancerGenomics, 2006
- C-Met antisense oligodeoxynucleotide inhibits growth of glioma cellsSurgical Neurology, 2006
- Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105Oncogene, 2005