Meropenem plus Ceftaroline Is Active against Enterococcus faecalis in an In Vitro Pharmacodynamic Model Using Humanized Dosing Simulations
- 18 October 2022
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 66 (10) , e0042622
Abstract
The standard of care for serious Enterococcus faecalis infections is ampicillin plus ceftriaxone. Ampicillin’s inconvenient dosing schedule, drug instability, allergy potential, along with ceftriaxone’s high risk for Clostridioides difficile infection and its promotion of vancomycin-resistant enterococci (VRE), led our team to explore alternative options.Keywords
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