Future prospects of accelerating neuroactive drug discovery with high-throughput behavioral phenotyping
- 27 January 2022
- journal article
- editorial
- Published by Taylor & Francis in Expert Opinion on Drug Discovery
- Vol. 17 (4) , 305-308
Abstract
In most therapeutic areas, the reverse chemical biology paradigms that utilize well-known molecular targets to develop specific treatments have become a standard approach in contemporary drug disco...Keywords
This publication has 20 references indexed in Scilit:
- Phenotypic screens as a renewed approach for drug discoveryDrug Discovery Today, 2013
- Behavioral barcoding in the cloud: embracing data-intensive digital phenotyping in neuropharmacologyTrends in Biotechnology, 2012
- Chemical informatics and target identification in a zebrafish phenotypic screenNature Chemical Biology, 2011
- Using the Zebrafish Photomotor Response for Psychotropic Drug Screening2011
- Development of automated imaging and analysis for zebrafish chemical screens.Journal of Visualized Experiments, 2010
- Fishing for neuroactive compoundsNature Chemical Biology, 2010
- Rapid behavior-based identification of neuroactive small molecules in the zebrafishNature Chemical Biology, 2010
- Automated image‐based phenotypic analysis in zebrafish embryosDevelopmental Dynamics, 2009
- Chemobehavioural phenomics and behaviour-based psychiatric drug discovery in the zebrafishBriefings in Functional Genomics and Proteomics, 2008
- In vivo drug discovery in the zebrafishNature Reviews Drug Discovery, 2005