“Evaluation of The Impact of Favipiravir Therapy on Laboratory Parameters in Patients with Chronic Kidney Disease Diagnosed with COVID-19” : A Retrospective Sin- gle Centre Study
Open Access
- 12 January 2026
- journal article
- Published by LookUs Bilisim A.S. in Medical Records
- No. 1
Abstract
Aim: Favipiravir, initially developed for influenza, is a potential treatment for COVID-19. However, safety data for favipiravir in patients with chronic renal failure is limited. This study examined its effects on laboratory parameters in COVID-19 patients both with and without chronic kidney disease (CKD), addressing the challenges posed by renal health impairment.Material and Methods: This retrospective study examined 339 eligible PCR-positive COVID-19 inpatients, selected from an initial 559 participants, at a Turkish tertiary care hospital. The patients were grouped based on estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m² and ≥ 60 mL/min/1.73 m² (control group). Clinical, demographic, and laboratory characteristics were compared using parametric and nonparametric tests, with statistical significance set at pKeywords
This publication has 15 references indexed in Scilit:
- STUDY OF EFFECTIVENESS AND SIDE EFFECTS OF FAVIPIRAVIR THERAPY ON MILD AND MODERATE COVID-19 PATIENTSJurnal Kesehatan, 2022
- Adverse effects associated with favipiravir in patients with COVID-19 pneumonia: a retrospective studySao Paulo Medical Journal, 2022
- Evaluation of risk factors for uric acid elevation in COVID-19 patients treated with favipiravirDiagnostic Microbiology and Infectious Disease, 2022
- The safety profile of favipiravir in COVID-19 patients with severe renal impairmentInternational Journal Of Clinical Practice, 2021
- Early favipiravir treatment was associated with early defervescence in non-severe COVID-19 patientsJournal of Infection and Chemotherapy, 2021
- Favipiravir Use in Kidney Transplant Recipients with Covid 19: A Single Center Experience2021
- Favipiravir and COVID-19: A Simplified SummaryDrug Research, 2020
- Favipiravir at high doses has potent antiviral activity in SARS-CoV-2−infected hamsters, whereas hydroxychloroquine lacks activityProceedings of the National Academy of Sciences, 2020
- Favipiravir: Pharmacokinetics and Concerns About Clinical Trials for 2019‐nCoV InfectionClinical Pharmacology & Therapeutics, 2020
- The effects of favipiravir on hematological parameters of covıd-19 patientsRevista da Associação Médica Brasileira, 2020