Chemotherapy in conjoint aging-tumor systems: some simple models for addressing coupled aging-cancer dynamics
Open Access
- 15 June 2010
- journal article
- Published by Springer Nature in Theoretical Biology and Medical Modelling
- Vol. 7 (1) , 21
Abstract
In this paper we consider two approaches to examining the complex dynamics of conjoint aging-cancer cellular systems undergoing chemotherapeutic intervention. In particular, we focus on the effect of cells growing conjointly in a culture plate as a precursor to considering the larger multi-dimensional models of such systems. Tumor cell growth is considered from both the logistic and the Gompertzian case, while normal cell growth of fibroblasts (WI-38 human diploid fibroblasts) is considered as logistic only.Keywords
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