The Role of Cognitive Functioning in Medication Adherence of Children and Adolescents with HIV Infection
Authors:
Open Access
- 24 June 2008
- journal article
- research article
- Published by Oxford University Press (OUP) in Journal of Pediatric Psychology
- Vol. 34 (2) , 164-175
Abstract
Objective To evaluate the relationship between cognitive functioning and medication adherence in children and adolescents with perinatally acquired HIV infection. Methods Children and adolescents, ages 3–18 (N = 1,429), received a cognitive evaluation and adherence assessment. Multiple logistic regression models were used to identify associations between adherence and cognitive status, adjusting for potential confounding factors. Results Children's average cognitive performance was within the low-average range; 16% of children were cognitively impaired (MDI/FSIQ Conclusion Cognitive status plays a limited role in medication adherence. Child and caregiver psychosocial and health characteristics should inform interventions to support adherence.Keywords
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