CT detection of demyelinated plaques in multiple sclerosis

Authors:
  • VHVm Haughton
    Vm Haughton
  • KHKc Ho
    Kc Ho
  • AWAL Williams
    AL Williams
  • OEOp Eldevik
    Op Eldevik
  • KHKc Ho Vm Haughton
    Kc Ho Vm Haughton
  • SSSm Spiegel
    Sm Spiegel
  • FVF Vinuela
    F Vinuela
  • AFAj Fox
    Aj Fox
  • DPDm Pelz
    Dm Pelz
  • CGCurtis A. Given
    Curtis A. Given
  • BSB. Scott Stevens
    B. Scott Stevens
  • CLCharles Lee
    Charles Lee
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Abstract
CT images and anatomic slices of two brains containing numerous demyelinated plaques were correlated. Demyelinated plaques smaller than 0.7 cm were not detected by CT. Some larger plaques were misinterpreted as normal structures. These and other considerations suggest that chronic cerebral demyelination cannot be excluded by negative nonenhanced CT scan.