Perineural Epithelium: A New Concept of its Role in the Integrity of the Peripheral Nervous System

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Abstract
A multilayered, squamous-celled epithelial cell membrane covering the individual nerve fasciculi of the entire peripheral nervous system (both voluntary and autonomic) including the sensory and motor end organs has been demonstrated in various species of animals, including man. This membrane is the direct continuation of the pia-arachnoid mater from the central nervous system. Functional significance of this membrane, especially as a diffusion barrier and as a protector of the peripheral nervous system, is briefly discussed.

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