A Shh/Gli-driven three-node timer motif controls temporal identity and fate of neural stem cells
Authors:
- José M. DiasJDJosé M. Dias
- Zhanna AlekseenkoZAZhanna Alekseenko
- Ashwini JeggariAJAshwini Jeggari
- Marcelo BoaretoMBMarcelo Boareto
- Jannik VollmerJVJannik Vollmer
- Mariya KozhevnikovaMKMariya Kozhevnikova
- Hui WangHWHui Wang
- Michael P. MatiseMMMichael P. Matise
- Andrey AlexeyenkoAAAndrey Alexeyenko
- Dagmar IberDIDagmar Iber
- Johan EricsonJEJohan Ericson
Open Access
- 18 September 2020
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science Advances
- Vol. 6 (38) , eaba8196
Abstract
A Shh/Gli-driven incoherent feed-forward loop circuit encodes time and counterbalances noise in temporal neural patterning.Keywords
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Funding Information
- Hjärnfonden (FO2017-0037)
- Karolinska Institutet
- Swedish Research Council for Health, Working Life and Welfare (2013-4155)
- Swedish Research Council for Health, Working Life and Welfare (2017-02089)
- Swedish Cancer Society (CAN2011/748)
- The Swedish Foundation for Strategic Research (SRL10-0030)
- Knut and Alice Wallenberg Foundation (KAW2011.0661)
- Knut and Alice Wallenberg Foundation (KAW2012.0101)
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