Prognostic and predictive value of nuclear imaging in endocrine oncology
- 16 November 2019
- journal article
- review article
- Published by Springer Nature in Endocrine
- Vol. 67 (1) , 9-19
Abstract
In the last few years, the role and use of medical technologies in (neuro)endocrine oncology has greatly evolved allowing not only important diagnostic information but also prognostic stratification in different clinical situations. The terms “prognostic” and “predictive” are commonly used to describe the relationships between biomarkers and patients’ clinical outcomes but have quite different meaning. The present work discusses the prognostic and predictive value of nuclear medicine imaging. It critically reviews the clinical significance and potential impact of molecular examinations on follow-up and therapeutic strategies in patients with neuroendocrine neoplasms, thyroid tumors, and adrenal malignancies.Keywords
This publication has 75 references indexed in Scilit:
- Peptide receptor radionuclide therapy of neuroendocrine tumors with 90Y-DOTATOC: Is treatment response predictable by pre-therapeutic uptake of 68Ga-DOTATOC?Diagnostic and Interventional Imaging, 2014
- The Role of Fluorine-18-Fluorodeoxyglucose Positron Emission Tomography in Aggressive Histological Subtypes of Thyroid Cancer: An OverviewInternational Journal of Endocrinology, 2013
- Prognosis Research Strategy (PROGRESS) 2: Prognostic Factor ResearchPLOS Medicine, 2013
- Detection Rate of Recurrent Medullary Thyroid Carcinoma Using Fluorine-18 Dihydroxyphenylalanine Positron Emission TomographyAcademic Radiology, 2012
- Predictive and prognostic factors for treatment and survival in 305 patients with advanced gastrointestinal neuroendocrine carcinoma (WHO G3): The NORDIC NEC studyAnnals of Oncology, 2012
- Nuclear medicine imaging of gastro-entero-pancreatic neuroendocrine tumors. The key role of cellular differentiation and tumor grade: from theory to clinical practiceCancer Imaging, 2012
- Do histological, immunohistochemical, and metabolic (radioiodine and fluorodeoxyglucose uptakes) patterns of metastatic thyroid cancer correlate with patient outcome?Endocrine-Related Cancer, 2010
- 18F-Fluorodeoxyglucose Positron Emission Tomography Predicts Survival of Patients with Neuroendocrine TumorsClinical Cancer Research, 2010
- Assessment of the Incremental Value of Recombinant Thyrotropin Stimulation before 2-[18F]-Fluoro-2-Deoxy-d-Glucose Positron Emission Tomography/Computed Tomography Imaging to Localize Residual Differentiated Thyroid CancerThe Journal of Clinical Endocrinology & Metabolism, 2009
- Prognostic factors versus predictive factors: Examples from a clinical trial of erlotinibMolecular Oncology, 2007