A Randomized Trial Comparing Ticlopidine Hydrochloride with Aspirin for the Prevention of Stroke in High-Risk Patients

Authors:
  • JEJ. Donald Easton
    J. Donald Easton
  • HAHarold P. Adams
    Harold P. Adams
  • WPWilliam Pryse-Phillips
    William Pryse-Phillips
  • BMBasil A. Molony
    Basil A. Molony
  • SASharon Anderson
    Sharon Anderson
  • BKBarbara Kamm
    Barbara Kamm
  • FGfor the Ticlopidine Aspirin Stroke Study Group
    for the Ticlopidine Aspirin Stroke Study Group
Publisher website
Google Scholar
Abstract
We report the results of the Ticlopidine Aspirin Stroke Study, a blinded trial at 56 North American centers that compared the effects of ticlopidine hydrochloride (500 mg daily) with those of aspirin (1300 mg daily) on the risk of stroke or death. The medications were randomly assigned to 3069 patients with recent transient or mild persistent focal cerebral or retinal ischemia. Follow-up lasted for two to six years.

This publication has 29 references indexed in Scilit: