Guidelines for the Treatment of Laryngeal Cancer from the Korean Society of Head and Neck Surgery
Authors:
- Jeon Yeob JangJJJeon Yeob Jang
- Geun-Jeon KimGKGeun-Jeon Kim
- Sang-Yeon KimSKSang-Yeon Kim
- Dong Kun LeeDLDong Kun Lee
- Minsu KwonMKMinsu Kwon
- Dongbin AhnDongbin Ahn
- Myung Jin BanMBMyung Jin Ban
- Young KangYKYoung Kang
- Ho-Ryun WonHWHo-Ryun Won
- Jae Won ChangJCJae Won Chang
- Dong Won LeeDLDong Won Lee
- Ki Nam ParkKPKi Nam Park
Open Access
- 31 May 2025
- journal article
- guideline
- Published by Korean Society of Otorhinolaryngology-Head and Neck Surgery in Clinical and Experimental Otorhinolaryngology
- Vol. 18 (2) , 89-108
Abstract
Objectives. Effective treatment of laryngeal cancer requires clinical decision-making that balances survival outcomes with the preservation of essential functions, such as voice and swallowing. This study, led by the Clinical Practice Guideline Committee of the Korean Society of Head and Neck Surgery, aims to establish evidence-based recommendations to guide surgeons in optimizing treatment decisions for patients with laryngeal cancer.Methods. A literature search was performed in the PubMed, Embase, Cochrane Library, and KoreaMed databases by a literature search expert and subsequently reviewed by a panel of 39 committee experts. The Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) method was employed to assess the quality of evidence and develop and report the recommendations. The strength of each recommendation reflects the guideline panel’s confidence that the benefits of an intervention outweigh its risks for the target population. After drafting the guidelines, Delphi questionnaires were distributed to members of the Korean Society of Head and Neck Surgery and an external reviewer panel.Results. In total, 15 evidence-based recommendations are provided, addressing six critical aspects of laryngeal cancer treatment: early-stage treatment, treatment of locally advanced cancer, neck management, adjuvant therapy, swallowing rehabilitation, and salvage treatment for recurrent tumors.Conclusion. The guidelines provide evidence-based, validated recommendations to support clinicians in making optimal treatment decisions for laryngeal cancer.Keywords
Funding Information
- National Cancer Center (NCC-2112570)
This publication has 235 references indexed in Scilit:
- Elective neck dissection in the treatment of T3/T4 N0 squamous cell carcinoma of the larynxThe American Journal of Surgery, 1995
- Squamous cell carcinomas of the aryepiglottic fold: Therapeutic results and long‐term follow‐upThe Laryngoscope, 1995
- Mechanisms of Recovery of Swallow After Supraglottic LaryngectomyJournal of Speech, Language, and Hearing Research, 1994
- Induction Chemotherapy plus Radiation Compared with Surgery plus Radiation in Patients with Advanced Laryngeal CancerNew England Journal of Medicine, 1991
- Laser cordectomy for T1 glottic carcinoma: A 10‐year experience and videostroboscopic findingsOtolaryngology–Head and Neck Surgery, 1991
- Stage T1 glottic carcinoma: results of radiation therapy or laser excision.Radiology, 1990
- Patterns of Cervical Node Metastases From Squamous Carcinoma of the LarynxJAMA Otolaryngology–Head & Neck Surgery, 1990
- The problem of neck relapse in early stage supraglottic cancer—Results of different treatment modalities for the clinically negative neckInternational Journal of Radiation Oncology - Biology - Physics (IJROBP), 1987
- Examination of swallowing after total laryngectomy using manofluorographyHead & Neck Surgery, 1986
- Laryngeal Spaces and Lymphatics: Current Anatomic ConceptsAnnals of Otology, Rhinology & Laryngology, 1983