Labeling of Hyaluronic Acids with a Rhenium-tricarbonyl Tag and Percutaneous Penetration Studied by Multimodal Imaging

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Abstract
Hyaluronic acids were labeled with a Single Core Multimodal Probe for Imaging (SCoMPI) and their penetration into human skin biopsies was studied using both IR microscopy and fluorescence imaging. The penetration was shown to be dependent on the molecular weight of the molecule and limited to the upper layer of the skin.
Funding Information
  • ?cole Normale Sup?rieure
  • Universit? Pierre et Marie Curie
  • Agence Nationale de la Recherche (ANR-10-IDEX-0001-02-PSL)
  • Centre National de la Recherche Scientifique

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