Different effects of influenza virus, respiratory syncytial virus, and Sendai virus on human lymphocytes and macrophages
Author:
- N J RobertsNRN J Roberts
- 1 March 1982
- journal article
- research article
- Published by American Society for Microbiology in Infection and Immunity
- Vol. 35 (3) , 1142-1146
Abstract
Influenza virus, respiratory syncytial virus, and Sendai virus depress human cell-mediated immune responses, such as mitogen-induced lymphocyte transformation, but differ in their ability to induce other immune defense mechanisms, such as interferon production. Exposure to the different viruses resulted in depressed transformation responses to the mitogen phytohemagglutinin by affecting the function of lymphocytes, or macrophages, or both cell types.Keywords
This publication has 23 references indexed in Scilit:
- Variability of Results of Lymphocyte Transformation Assays in Normal Human Volunteers: Responses of Mononuclear Leukocytes to Mitogen StimulationAmerican Journal of Clinical Pathology, 1980
- Mitogen responses and interferon production after exposure of human macrophages to infectious and inactivated influenza virusesJournal of Medical Virology, 1980
- The pathogenesis of respiratory viral infectionPostgraduate Medical Journal, 1979
- Clinical Trials with Exogenous Interferon: Summary of a MeetingThe Journal of Infectious Diseases, 1979
- Effect of in Vitro Virus Infection on Response of Human Monocytes and Lymphocytes to Mitogen StimulationThe Journal of Immunology, 1978
- Defect in intracellular killing of Staphylococcus aureus within alveolar macrophages in Sendai virus-infected murine lungs.Journal of Clinical Investigation, 1976
- Infection, Anergy and Cell-Mediated ImmunityNew England Journal of Medicine, 1975
- T-LYMPHOCYTE INTERACTION WITH VIRUSES AND VIRUS-INFECTED TISSUES1975
- Inactivation of Myxoviruses by Lymphoid CellsJournal of General Virology, 1973
- Effect of Virus Infections on the Function of the Immune SystemAnnual Review of Microbiology, 1970