Synthesis, characterization, DNA interaction, and anticancer studies of novel facial tricarbonylrhenium( i ) complexes with uracil-derived ligands
Open Access
- 17 September 2025
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in RSC Advances
- Vol. 15 (41) , 34635-34642
Abstract
A series of facial tricarbonylrhenium( i ) complexes with uracil-derived bidentate chelators was characterized by various physicochemical techniques. The most cytotoxic metal complex exhibits dual DNA intercalation and groove binding capabilities.Keywords
Funding Information
- South African Agency for Science and Technology Advancement (190403426633)
- South African Agency for Science and Technology Advancement (94020)
- South African Nuclear Energy Corporation
- Rhodes University
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