High-Density and Large-Scale MEA System Featuring 236,880 Electrodes at 11.72μm Pitch for Neuronal Network Analysis

Authors:

1 June 2020

conference paper
Published by Institute of Electrical and Electronics Engineers (IEEE)

p. 1-2
DOI:10.1109/vlsicircuits18222.2020.9162947

Abstract

Microelectrode arrays (MEAs) allow us to observe electrical activities from neurons at multiple sites. This paper presents a high-density microelectrode array (HD-MEA) for observing neuronal networks at a cellular level, featuring 236,880 electrodes at an 11.72 μm pitch and 33,840 readout channels with a noise level of 5.5 μVrms. The Peltier cooling system is integrated to maintain the temperature of the electrodes at approximately 37 °C. Moreover, electrical signals for the axonal propagation of rat neurons are successfully recorded.

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This publication has 1 reference indexed in Scilit:

A 4.8-μVrms-Noise CMOS-Microelectrode Array With Density-Scalable Active Readout Pixels via Disaggregated Differential Amplifier Implementation
Frontiers in Neuroscience, 2019