Abstract
Methods Our review is based on information from the annual reports of Serious Hazards of Transfusion (www.shot.demon.co.uk/), the guidelines of the British Committee for Standards in Haematology (www.bcshguidelines.com/), and the chief medical officer's second “Better Blood Transfusion” meeting (www.doh.gov.uk/bbt2). We also cite relevant recent publications by leading clinicians and scientists.