INDUCTION OF TOLERANCE TO SHEEP RED BLOOD CELLS
Authors:
Open Access
- 1 December 1972
- journal article
- Published by Rockefeller University Press in Journal of Experimental Medicine
- Vol. 136 (6) , 1666-1671
Abstract
Adult mice injected with a sheep red blood cell hemolysate supernatant fraction were found to have a severely reduced responsiveness to subsequent immunization with sheep red blood cells. The induced unresponsiveness was found to be specific, as tested by reciprocal experiments involving horse and sheep erythrocyte preparations. The tolerogenic material did not appear to be immunogenic.Keywords
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