Abstract
Purpose: To evaluate the clinical outcomes of aspheric ocular wavefront ablation profiles in LASIK treatments. Methods: Thirty eyes treated by ocular wavefront were retrospectively analyzed at 6-month follow-up. Custom Ablation Manager (CAM) software was used to plan wavefront-customized aspheric treatments, and the ESIRIS system was used to perform ablations (SCHWIND eye-tech-solutions). Outcomes were evaluated in terms of efficacy, predictability, refractive outcome, safety, and pre- and postoperative wavefront aberration analysis (SCHWIND Ocular Wavefront Analyzer). Results: At 6 months postoperatively, 47% of eyes achieved uncorrected visual acuity 20/20 or better. Average defocus was reduced from −3.49±2.38 diopters (D) preoperatively (range: −10.63 to 0.00 D) to −0.14±0.31 D postoperatively (range: −1.75 to 0.00 D). Astigmatism was reduced from −0.81±1.15 D (range: −4.25 to 0.00 D) to −0.25±0.37 D (range: −1.25 to 0.00 D). Eighty-six percent of eyes were within ±0.50 D. Best spectacle-corrected visual acuity (logMAR) improved from +0.12±0.08 (range: 0.0 to +0.2) to −0.05±0.13 (range: −0.2 to +0.2) ( P =.04). The treatment did not change coma or spherical aberration, and reduced the trefoil from 0.21±0.13 µm (range: 0.05 to 0.53 µm) to 0.08±0.13 µm (range: 0.01 to 0.39 µm) ( P =.002). Conclusions: The study results indicate that the aspheric ocular wavefront customized CAM approach for planning ablation volumes is safe and effective. [ J Refract Surg . 2009;25:1083–1090.]

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