Combinatorial synthesis — the design of compound libraries and their application to drug discovery
Authors:
- Nicholas K. TerrettNTNicholas K. Terrett
- Mark GardnerMGMark Gardner
- David W. GordonDGDavid W. Gordon
- Ryszard J. KobyleckiRKRyszard J. Kobylecki
- John SteeleJSJohn Steele
- 1 July 1995
- journal article
- Published by Elsevier in Tetrahedron
- Vol. 51 (30) , 8135-8173
Abstract
No abstract availableKeywords
This publication has 66 references indexed in Scilit:
- The combinatorial synthesis of a 30,752-compound library: discovery of SAR around the endothelin antagonist, FR-139,317Bioorganic & Medicinal Chemistry Letters, 1995
- A Novel and Versatile Silicon-Derived Linkage Agent, 4-[1-Hydroxy-2-(trimethylsilyl)ethyl]benzoic Acid, Compatible with the Fmoc/t-Bu Strategy for Solid Phase Synthesis of C-Terminal Peptide AcidsJournal of the American Chemical Society, 1994
- Multipin peptide synthesis at the micromole scale using 2‐hydroxyethyl methacryiate grafted polyethylene supportsInternational Journal of Peptide and Protein Research, 1993
- Synthetic peptide combinatorial libraries (SPCLs): identification of the antigenic determinant of β-endorphin recognized by monoclonal antibody 3E7Gene, 1993
- The use of positional scanning synthetic peptide combinatorial libraries for the rapid determination of opioid receptor ligandsLife Sciences, 1993
- Paleobiogeography of the Ancient PacificScience, 1990
- Acid‐labile anchoring linkages for solid phase synthesis of C‐terminal asparagine peptides using the Fmoc strategyInternational Journal of Peptide and Protein Research, 1990
- Random Peptide Libraries: a Source of Specific Protein Binding MoleculesScience, 1990
- Solid phase peptide synthesis utilizing 9‐fluorenylmethoxycarbonyl amino acidsInternational Journal of Peptide and Protein Research, 1990
- Solid Phase Peptide Synthesis. I. The Synthesis of a TetrapeptideJournal of the American Chemical Society, 1963