High-throughput cryo-EM structure determination of amyloids
Open Access
- 1 January 2022
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Faraday Discussions
- Vol. 240, 243-260
Abstract
This paper presents new cryo-EM image processing methods for amyloids, including automated picking and strategies for helical structure determination in RELION. The image shows examples of tau filament structures that were solved using these methods.Keywords
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Funding Information
- Medical Research Council (MC_UP_A025_1013)
- UK Research and Innovation
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