Target identification and validation of natural products with label-free methodology: A critical review from 2005 to 2020
- 1 December 2020
- journal article
- review article
- Published by Elsevier in Pharmacology & Therapeutics
- Vol. 216, 107690
Abstract
No abstract availableKeywords
Funding Information
- National Natural Science Foundation of China (81902787)
- Swedish Research Council
- Swedish Cancer Society
- Knut and Alice Wallenberg Foundation
- National Research Foundation
This publication has 196 references indexed in Scilit:
- Target Identification Using Drug Affinity Responsive Target Stability (DARTS)Current Protocols in Chemical Biology, 2011
- Thermodynamic Analysis of Protein–Ligand Interactions in Complex Biological Mixtures using a Shotgun Proteomics ApproachJournal of Proteome Research, 2011
- Energetics-Based Discovery of Protein–Ligand Interactions on a Proteomic ScaleJournal of Molecular Biology, 2011
- Identification of Direct Protein Targets of Small MoleculesACS Chemical Biology, 2010
- Reactive oxygen species mediate hepatotoxicity induced by the Hsp90 inhibitor geldanamycin and its analogsFree Radical Biology and Medicine, 2010
- Natural Products as Chemical ProbesACS Chemical Biology, 2010
- Molecular Crowding Inhibits Intramolecular Breathing Motions in ProteinsJournal of Molecular Biology, 2008
- Energetics-based Protein Profiling on a Proteomic Scale: Identification of Proteins Resistant to ProteolysisJournal of Molecular Biology, 2007
- Property Distributions: Differences between Drugs, Natural Products, and Molecules from Combinatorial ChemistryJournal of Chemical Information and Computer Sciences, 2002
- Atomic Structures of the Human Immunophilin FKBP-12 Complexes with FK506 and RapamycinJournal of Molecular Biology, 1993