PMS2 and POLR2J gene families as molecular markers of the higher primates evolution
- 30 September 2010
- journal article
- research article
- Published by Pleiades Publishing Ltd in Russian Journal of Genetics
- Vol. 46 (9) , 1112-1114
Abstract
We have studied the molecular evolution of two gene families specific for primates: POLR2J of the transcription system and PMS2 of the mismatch repair (MMR) system. The appearance of these families and upgrading of their genetic structures was shown to neatly correlate with the main stages of the biological evolution of higher primates. Our results indicate that the PMS2 and POLR2J genes can serve as helpful and reliable molecular markers of anthropogenesis.Keywords
This publication has 9 references indexed in Scilit:
- Human-specific transcriptional regulation of CNS development genes by FOXP2Nature, 2009
- A burst of segmental duplications in the genome of the African great ape ancestorNature, 2009
- Human-Specific Gain of Function in a Developmental EnhancerScience, 2008
- Microcephalin , a Gene Regulating Brain Size, Continues to Evolve Adaptively in HumansScience, 2005
- Evolution of the HumanASPMGene, a Major Determinant of Brain SizeGenetics, 2003
- Birth of ‘Human-Specific’ Genes During Primate EvolutionGenetica, 2003
- When Less Is More: Gene Loss as an Engine of Evolutionary ChangeThe American Journal of Human Genetics, 1999
- The Origin of Man: A Chromosomal Pictorial LegacyScience, 1982
- Evolution at Two Levels in Humans and ChimpanzeesScience, 1975