Percutaneous Patent Ductus Arteriosus (PDA) Closure in Very Preterm Infants: Feasibility and Complications

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Abstract
Background: Percutaneous closure of patent ductus arteriosus ( PDA ) in term neonates is established, but data regarding outcomes in infants born very preterm (P <0.01). Conclusions: Among infants born very preterm, percutaneous PDA closure at weights <4 kg is generally safe and may improve respiratory health, but risk of arterial injury is noteworthy. Randomized clinical trials are needed to assess clinically relevant differences in outcomes following percutaneous PDA closure versus alternative (surgical ligation) management strategies.

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