SPONTANEOUS ANTIBODY-SECRETING HUMAN-BLOOD LYMPHOCYTES DETECTED WITH A PROTEIN-A PLAQUE-ASSAY
Authors:
- T KunoriTKT Kunori
- P BromanPBP Broman
- M TanMTM Tan
- 1 January 1980
- journal article
- research article
- Vol. 42 (1) , 162-166
Abstract
Spontaneous antibody-secreting lymphocytes in human peripheral blood were detected and counted by a [Staphylococcus aureus] protein A plaque assay. The level of plaque-forming cells (PFC) in peripheral blood was significantly higher in patients with immune disorders (per 106 lymphocytes: IgG PFC, 2654 .+-. 684; IgA PFC, 1727 .+-. 327; IgM PFC, 403 .+-. 92) than in normal controls (per 106 lymphocytes: IgG PFC, 327 .+-. 56; IgA PFC 633 .+-. 128; IgM PFC, 215 .+-. 105). There was no direct correlation between the PFC numbers of different Ig classes.Keywords
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