Housekeeping while brain's storming Validation of normalizing factors for gene expression studies in a murine model of traumatic brain injury
Open Access
- 1 January 2008
- journal article
- Published by Springer Nature in BMC Molecular Biology
- Vol. 9 (1) , 62
Abstract
Traumatic brain injury models are widely studied, especially through gene expression, either to further understand implied biological mechanisms or to assess the efficiency of potential therapies. A large number of biological pathways are affected in brain trauma models, whose elucidation might greatly benefit from transcriptomic studies. However the suitability of reference genes needed for quantitative RT-PCR experiments is missing for these models.Keywords
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