Impaired platelet‐dependent thrombin generation associated with thrombocytopenia is improved by prothrombin complex concentrates in vitro
Open Access
- 14 February 2020
- journal article
- research article
- Published by Elsevier in Research and Practice in Thrombosis and Haemostasis
- Vol. 4 (2) , 334-342
Abstract
No abstract availableKeywords
Funding Information
- Royal Free Charity (TF35)
- CSL Behring
This publication has 37 references indexed in Scilit:
- Tissue factor–dependent thrombin generation across pregnancyAmerican Journal of Obstetrics and Gynecology, 2012
- First-line Therapy with Coagulation Factor Concentrates Combined with Point-of-Care Coagulation Testing Is Associated with Decreased Allogeneic Blood Transfusion in Cardiovascular SurgeryAnesthesiology, 2011
- Effects of tranexamic acid on death, vascular occlusive events, and blood transfusion in trauma patients with significant haemorrhage (CRASH-2): a randomised, placebo-controlled trialThe Lancet, 2010
- Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogramThrombosis and Haemostasis, 2009
- Influence of coagulation factors and tissue factor concentration on the thrombin generation test in plasmaThrombosis and Haemostasis, 2008
- Pharmacokinetics of Beriplex P/N prothrombin complex concentrate in healthy volunteersThrombosis and Haemostasis, 2007
- Platelet-dependent thrombin generation assay for monitoring the efficacy of recombinant Factor VIIaPlatelets, 2005
- Efficacy of standard dose and 30 ml/kg fresh frozen plasma in correcting laboratory parameters of haemostasis in critically ill patientsBritish Journal of Haematology, 2004
- The role of platelets and recombinant factor VIIa on thrombin generation, platelet activation and clot formationThrombosis and Haemostasis, 2004
- Clinical Experience with Recombinant Factor VIla in Patients with ThrombocytopeniaPathophysiology of Haemostasis and Thrombosis, 1996