Vital signs and cognitive function are not affected by 23‐sodium and 17‐oxygen magnetic resonance imaging of the human brain at 9.4 T

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Abstract
Purpose: To evaluate the effect of 23‐sodium (23Na) and 17‐oxygen (17O) magnetic resonance imaging (MRI) at 9.4 (T) on vital signs and cognitive function of the human brain.Materials and Methods: Vital sign and cognitive function measurements from healthy volunteers (N = 14) positioned outside and at isocenter of a 9.4 T scanner before and after 23Na and 17O MRI were compared for changes due to exposure to the static magnetic field and to the gradient switching and radiofrequency radiation during MRI.Results: Exposure to the 9.4 T static magnetic field and 23Na and 17O MRI at 105.92 MHz and 54.25 MHz, respectively, did not have a statistically significant (P > 0.05) effect on the vital signs or cognitive function of healthy normal adults.Conclusion: 23Na and 17O MRI of the human brain at 9.4 T does not have any readily demonstrated health risks reflected in vital signs or change in cognitive performance. J. Magn. Reson. Imaging 2010;32:82–87.

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