A Comparison of Tacrolimus (FK 506) and Cyclosporine for Immunosuppression in Liver Transplantation
Author:
- The U.S. Multicenter FK506 Liver Study GroupTGThe U.S. Multicenter FK506 Liver Study Group
- 27 October 1994
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 331 (17) , 1110-1115
Abstract
Tacrolimus (FK 506), a macrolide compound isolated from a bacterium, is a potent immunosuppressant with activity in solid-organ transplants. Most immunosuppressive regimens for liver transplantation are based on cyclosporine.Keywords
This publication has 8 references indexed in Scilit:
- Randomised trial comparing tacrolimus (FK506) and cyclosporin in prevention of liver allograft rejectionThe Lancet, 1994
- Liver TransplantationNew England Journal of Medicine, 1989
- STUDIES OF THE EFFECTS OF FK506 ON RENAL ALLOGRAFTING IN THE BEAGLE DOGTransplantation, 1987
- FK-506, a novel immunosuppressant isolated from a Streptomyces. II. Immunosuppressive effect of FK-506 in vitro.The Journal of Antibiotics, 1987
- FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.The Journal of Antibiotics, 1987
- Cyclosporine nephrotoxicityKidney International, 1986
- Analysis of Liver TransplantationHepatology, 1984
- Nonparametric Estimation from Incomplete ObservationsJournal of the American Statistical Association, 1958