Alcohol Dehydrogenase in Drosophila melanogaster : Isozymes and Genetic Variants

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Abstract
Alcohol dehydrogenase, in Drosophila melanogaster homozygous for the alleles Adh F or Adh S , is found in three electrophoretically different forms. Adh F differs from Adh S in that isozymes with faster electrophoretic mobilities are present. In Adh F / Adh S heterozygotes, hybrid isozymes as well as the parental isozymes are present, indicating that the dehydrogenase may exist as a dimer of two polypeptide subunits. The gene, Adh , is located on the second chromosome, with a map position of 50.1 and a cytological position between 34E3 and 35D1.