Risk factors for recurrence following radical cystectomy for pathologic node negative bladder cancer

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Abstract
Background and Objectives: To evaluate for risk factors associated with bladder cancer recurrence in patients with pathologically negative lymph nodes.Methods: A retrospective review of 405 patients undergoing radical cystectomy for bladder cancer between 1996 and 2008 was performed. Patients with node‐positive disease and P = 0.01, 0.037, 0.038, respectively). There was no difference in 5‐year recurrence free survival when stratified by node yield using the Kaplan–Meier method (P = 0.138).Conclusions: We identified LVI, PNI, and lymph node yield <14 as three independent risk factors for bladder cancer recurrence in patients with node‐negative bladder cancer. J. Surg. Oncol. 2010;102:334–337.

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