The human thyrotropin receptor activates G-proteins Gs and Gq/11.
Authors:
- S. OffermannsSOS. Offermanns
- J. Van SandeJSJ. Van Sande
- K. SpicherKSK. Spicher
- G. SchultzGSG. Schultz
- J.E. DumontJDJ.E. Dumont
Open Access
- 1 May 1994
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 269 (19) , 13733-13735
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- The human and dog 5-HT1D receptors can both activate and inhibit adenylate cyclase in transfected cellsEuropean Journal of Pharmacology: Molecular Pharmacology, 1993
- Thyrotropin, Like Luteinizing Hormone (LH) and Chorionic Gonadotropin (CG), Increases cAMP and Inositol Phosphate Levels in Cells with Recombinant Human LH/CG ReceptorBiochemical and Biophysical Research Communications, 1993
- Receptor-to-effector signaling through G proteins: Roles for βγ dimers as well as α subunitsCell, 1992
- Isozyme-selective stimulation of phospholipase C-β2 by G protein βγ-subunitsNature, 1992
- Endothelin stimulates both cAMP formation and phosphatidylinositol hydrolysis in cultured embryonic bovine tracheal cellsFEBS Letters, 1992
- Type-Specific Regulation of Adenylyl Cyclase by G Protein βγ SubunitsScience, 1991
- Unlike thyrotropin, thyroid-stimulating antibodies do not activate phospholipase C in human thyroid slices.Journal of Clinical Investigation, 1991
- Thyrotropin activates both the cyclic AMP and the PIP2casades in CHO cells expressing the human cDNA of TSH receptorMolecular and Cellular Endocrinology, 1990
- Iodide‐induced inhibition of adenylate cyclase activity in horse and dog thyroidEuropean Journal of Biochemistry, 1987
- Dual activation by thyrotropin of the phospholipase C and cyclic AMP cascades in human thyroidMolecular and Cellular Endocrinology, 1987