Cloning and sequence analysis of cDNA encoding the precursor of a human endothelium‐derived vasoconstrictor peptide, endothelin: Identity of human and porcine endothelin
Authors:
- Masashi YanagisawaMYMasashi Yanagisawa
- Shoichi OhkuboSOShoichi Ohkubo
- Chiharu KimuraCKChiharu Kimura
- Takuo KosakaTKTakuo Kosaka
- Akihiro InoueAIAkihiro Inoue
- Norio IshidaNINorio Ishida
- Youji MitsuiYMYouji Mitsui
- Haruo OndaHOHaruo Onda
- Masahiko FujinoMFMasahiko Fujino
- Tomoh MasakiTMTomoh Masaki
- 25 April 1988
- journal article
- research article
- Published by Wiley in FEBS Letters
- Vol. 231 (2) , 440-444
Abstract
A cDNA encoding a human endothelium‐derived vasoconstrictor peptide, endothelin, was isolated from a human placenta cDNA library. The nucleotide sequence of this cDNA clone showed that the primary structure of the human preproendothelin has 212 amino acid residues and is highly homologous to porcine preproendothelin, and that human endothelin is identical with porcine endothelin.Keywords
This publication has 7 references indexed in Scilit:
- Heparan sulfate and heparin as a potentiator or a suppressor of growth of normal and transformed vascular endothelial cellsExperimental Cell Research, 1987
- A new method for predicting signal sequence cleavage sitesNucleic Acids Research, 1986
- Hybridization with Synthetic 32P End-Labeled Probe1986
- Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAsNucleic Acids Research, 1984
- Prediction of protein antigenic determinants from amino acid sequences.Proceedings of the National Academy of Sciences, 1981
- DNA sequencing with chain-terminating inhibitorsProceedings of the National Academy of Sciences, 1977
- Screening λgt Recombinant Clones by Hybridization to Single Plaques in SituScience, 1977