Cell division from a genetic perspective
Author:
- Lh HartwellLHLh Hartwell
Open Access
- 1 June 1978
- journal article
- review article
- Published by Rockefeller University Press in Journal of Cell Biology
- Vol. 77 (3) , 627-637
Abstract
A novel view of the eukaryotic cell cycle is taking form as genetic strategies borrowed from investigations of microbial gene regulation and bacteriophage morphogenesis are being applied to the process of cell division. It is a genetic construct in which mutational lesions identify the primary events, thermolabile gene products reveal temporal order, mutant phenotypes yield pathways of causality, and regulatory events are localized within sequences of gene controlled steps.Keywords
This publication has 48 references indexed in Scilit:
- Genetic control of cell division in yeast cultured at different growth ratesNature, 1977
- Causal relations among cell cycle processes in Tetrahymena pyriformis. An analysis employing temperature-sensitive mutants.Journal of Cell Biology, 1976
- Temperature-sensitive mutants of Balb/3T3 cells: Description of a mutant affected in cellular and polyoma virus DNA synthesisCell, 1976
- Genetic control of cell size at cell division in yeastNature, 1975
- Temperature-sensitive cell cycle mutants: a chinese hamster cell line with a reversible block in cytokinesisCell, 1975
- A temperature‐sensitive cell cycle mutant of the BHK cell lineJournal of Cellular Physiology, 1974
- A mammalian somatic “cell cycle” mutant defective in G1Journal of Cellular Physiology, 1974
- Isolation of temperature sensitive mammalian cells by selective detachmentJournal of Cellular Physiology, 1973
- CONDITIONAL MUTANTS IN CHLAMYDOMONAS REINHARDTII BLOCKED IN THE VEGETATIVE CELL CYCLEJournal of Cell Biology, 1973
- Synchronization of haploid yeast cell cycles, a prelude to conjugationExperimental Cell Research, 1973