Relief of duodenal ulcer sysmptons by oral metiamide.
Authors:
- R E PounderRPR E Pounder
- J G WilliamsJWJ G Williams
- G J Milton-ThompsonGMG J Milton-Thompson
- J J MisiewiczJMJ J Misiewicz
Abstract
Thirty patients with symptoms of duodenal ulceration were treated for five to eight weeks in a double-blind trial with either metiamide 1 g daily by mouth or a placebo. In the 15 patients receiving metiamide there were significant reductions in nocturnal pain and antacid consumption. Daytime pain was diminished. The results suggest that histamine H2-receptor antagonists are likely to be useful in the medical management of the symptoms of duodenal ulceration.Keywords
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