Spinal muscular atrophy: MR evaluation
Authors:
- 1 December 1992
- journal article
- Published by Springer Nature in Pediatric Radiology
- Vol. 22 (8) , 584-586
Abstract
The neurogenic myopathy of spinal muscular atrophy (SMA) is degeneration of anterior horn cells of the spinal cord and associated muscle weakness. In three patients with the severe type, according to Dubowitz's classification, magnetic resonance imaging (MRI) of the lower extremity showed severe atrophy of the entire muscle bundles of the thigh and the calf. Nine intermediate type patients had ragged atrophy of muscle bundles of the thigh and the calf with selective preservation of adductor longus muscle. Five patients with the mild type had fatty infiltration of muscle bundles and increased intermuscular fat planes. MRI was insufficient for the evaluation of cervical cord abnormalities. MRI of the lower extremity was a reliable complementary modality for the diagnosis and follow-up of SMA patients.Keywords
This publication has 14 references indexed in Scilit:
- Medical Malpractice and the Tort SystemJAMA, 1989
- MR imaging of the musculoskeletal system: a 5-year appraisal.Radiology, 1988
- Electromyographic and Computed Tomographic Findings in Five Patients with Monomelic Spinal Muscular AtrophyEuropean Neurology, 1988
- High resolution surface coil magnetic resonance imaging of the joints: anatomic correlation.RadioGraphics, 1987
- CT and the diagnosis of myopathiesNeuroradiology, 1986
- MRI of normal and pathologic skeletal muscleAmerican Journal of Roentgenology, 1986
- MR imaging with surface coils.Radiology, 1985
- Computed tomography of the skeletal musculature in Becker‐type muscular dystrophy and benign infantile spinal muscular atrophyMuscle & Nerve, 1985
- Comparison of CT and MR in 400 patients with suspected disease of the brain and cervical spinal cord.Radiology, 1984
- Computed Tomographic Patterns of Muscles in Neuromuscular DiseasesArchives of Neurology, 1984