Clinical and biochemical manifestations of Cushing’s
Authors:
- 10 January 2015
- journal article
- review article
- Published by Springer Nature in Pituitary
- Vol. 18 (2) , 181-187
Abstract
Cushing’s syndrome is associated with a number of clinical manifestations and co-morbidities which may not resolve even after long-term remission leading to excessive mortality. This review summarizes the main manifestations of Cushing’s syndrome (active or in remission) with particular focus on data from recently published literature. Obesity and metabolic alterations, hypertension and cardio/cerebrovascular complications, hypercoagulability/thromboembolism, neuropsychiatric, muscle/skeletal and immune consequences remain the most challenging. Cardiovascular consequences and immunosuppression determine the main causes of death in Cushing’s syndrome necessitating early intervention when possible.Keywords
This publication has 87 references indexed in Scilit:
- Exophthalmos: A Forgotten Clinical Sign of Cushing's SyndromeCase Reports in Endocrinology, 2013
- Hypercoagulable state in Cushing's syndrome is reversible following remissionClinical Endocrinology, 2012
- Body Composition and Cardiovascular Risk Markers after Remission of Cushing's Disease: A Prospective Study Using Whole-Body MRIThe Journal of Clinical Endocrinology & Metabolism, 2012
- Increased myocardial fibrosis and left ventricular dysfunction in Cushing's syndromeEuropean Journal of Endocrinology, 2012
- Impact of chronic hypercortisolemia on affective processingNeuropharmacology, 2012
- Diabetes in Cushing syndrome: basic and clinical aspectsTrends in Endocrinology & Metabolism, 2011
- Adipokines and Cardiovascular Risk in Cushing’s SyndromeNeuroendocrinology, 2011
- MRI assessment of lean and adipose tissue distribution in female patients with Cushing’s diseaseClinical Endocrinology, 2010
- Exacerbation of Autoimmune Thyroiditis Following Bilateral Adrenalectomy for Cushing's SyndromeThyroid®, 2010
- Patterns of cognitive change over time and relationship to age following successful treatment of Cushing's diseaseJournal of the International Neuropsychological Society, 2006