Stereoselective One-Pot, Three-Component Synthesis of 4-Aryltetrahydropyran via Prins−Friedel−Crafts Reaction
Authors:
- 13 February 2009
- journal article
- Published by American Chemical Society (ACS) in The Journal of Organic Chemistry
- Vol. 74 (6) , 2605-2608
Abstract
A diastereoselective one-pot, three-component Prins−Friedel−Crafts reaction was developed for the synthesis of 4-aryltetrahydropyran derivatives from the reaction of carbonyl compounds with homoallylic alcohol in the presence of arene promoted by boron trifluoride etherate.Keywords
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