TopBP1 deficiency impairs the localization of proteins involved in early recombination and results in meiotic chromosome defects during spermatogenesis
Authors:
- 1 January 2019
- journal article
- research article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 508 (3) , 722-728
Abstract
No abstract availableKeywords
Funding Information
- Basic Research Lab Program (2018R1A4A1025860)
- Global Frontier Project (2013M3A6A4045755)
- National Research Foundation, South Korea,
- National Cancer Center Grant (NCC-1710190, 1810042)
- South Korea government
This publication has 34 references indexed in Scilit:
- An Essential Function for the ATR-Activation-Domain (AAD) of TopBP1 in Mouse Development and Cellular SenescencePLOS Genetics, 2013
- MDC1 directs chromosome-wide silencing of the sex chromosomes in male germ cellsGenes & Development, 2011
- Distinct Properties of the XY Pseudoautosomal Region Crucial for Male MeiosisScience, 2011
- TopBP1 Deficiency Causes an Early Embryonic Lethality and Induces Cellular Senescence in Primary CellsJournal of Biological Chemistry, 2011
- Epigenetic Modifications in Double-Strand Break DNA Damage Signaling and RepairClinical Cancer Research, 2010
- Mouse HORMAD1 and HORMAD2, Two Conserved Meiotic Chromosomal Proteins, Are Depleted from Synapsed Chromosome Axes with the Help of TRIP13 AAA-ATPasePLOS Genetics, 2009
- TopBP1 and DNA polymerase-α directly recruit the 9-1-1 complex to stalled DNA replication forksJournal of Cell Biology, 2009
- Mutation of the Mouse Syce1 Gene Disrupts Synapsis and Suggests a Link between Synaptonemal Complex Structural Components and DNA RepairPLOS Genetics, 2009
- Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic miceGenesis, 2008
- The Rad9–Hus1–Rad1 (9–1–1) clamp activates checkpoint signaling via TopBP1Genes & Development, 2007