A Comparative Investigation of the Bactericidal and Fungicidal Effects of Three Phenolic Disinfectants
Author:
- 1 October 1977
- journal article
- research article
- Published by Wiley in Journal of Applied Bacteriology
- Vol. 43 (2) , 177-181
Abstract
Two methods, a capacity use‐dilution test and another employing geometrical dilution, are used when comparing the bactericidal and fungicidal effects of a phenolic disinfectant containing 45% (w/w) o ‐phenylphenol in an aqueous soap solution of linseed oil (soap content 6·5% w/v) with the corresponding effects of the same phenolic compound in an aqueous soya oil soap solution (soap content 3·5% w/v). The soya oil soap did not change the disinfectant capacity on the different test organisms used. For the most resistant strain ( Staphylococcus aureus ) the usedilution concentration was evaluated to be slightly above 1%, i.e. 2%, which is much lower than the recommended use‐dilution concentration. However, using the same method and test organisms the capacity use‐dilution testing of a third phenolic disinfectant, containing p ‐chloro‐ m ‐cresol and o ‐benzyl‐ p ‐chlorophenol with a total of 9·2 (w/w) phenols in a detergent system, indicated that the recommended use‐dilution concentration should be doubled.Keywords
This publication has 3 references indexed in Scilit:
- Comparative Study of Seven Media for Sterility TestingJournal of Pharmaceutical Sciences, 1974
- Disinfectant Evaluation by a Capacity Use‐dilution TestJournal of Applied Bacteriology, 1971
- The Influence of Soaps on the Bactericidal Activity of a Sparingly Water-Soluble PhenolJournal of Pharmacy and Pharmacology, 1956