Superparamagnetic Twist‐Type Actuators with Shape‐Independent Magnetic Properties and Surface Functionalization for Advanced Biomedical Applications
- 23 May 2014
- journal article
- research article
- Published by Wiley in Advanced Functional Materials
- Vol. 24 (33) , 5269-5276
Abstract
Directed nanoparticle self‐organization and two‐photon polymerization are combined to enable three‐dimensional soft‐magnetic microactuators with complex shapes and shape‐independent magnetic properties. Based on the proposed approach, single and double twist‐type swimming microrobots with programmed magnetic anisotropy are demonstrated, and their swimming properties in DI‐water are characterized. The fabricated devices are actuated using weak rotating magnetic fields and are capable of performing wobble‐free corkscrew propulsion. Single twist‐type actuators possess an increase in surface area in excess of 150% over helical actuators with similar feature size without compromising the forward velocity of over one body length per second. A generic and facile combination of glycine grafting and subsequent protein immobilization exploits the actuator's increased surface area, providing for a swimming microrobotic platform with enhanced load capacity desirable for future biomedical applications. Successful surface modification is confirmed by FITC fluorescence.Keywords
This publication has 31 references indexed in Scilit:
- Bio-inspired magnetic swimming microrobots for biomedical applicationsNanoscale, 2012
- Programming magnetic anisotropy in polymeric microactuatorsNature Materials, 2011
- A photopatternable superparamagnetic nanocomposite: Material characterization and fabrication of microstructuresSensors and Actuators B: Chemical, 2011
- Remote actuation of hydrogel nanocomposites: Heating analysis, modeling, and simulationsAIChE Journal, 2011
- Artificial bacterial flagella for micromanipulationLab on a Chip, 2010
- New Technologies for Human Cancer ImagingJournal of Clinical Oncology, 2008
- Fabrication of magnetic micromachine for local hyperthermiaIEEE Transactions on Magnetics, 2002
- The operation of a magnetic micromachine for hyperthermia and its exothermic characteristicIEEE Transactions on Magnetics, 2002
- Adsorption of proteins onto surfaces containing end-attached oligo(ethylene oxide): a model system using self-assembled monolayersJournal of the American Chemical Society, 1993
- Bacteria Swim by Rotating their Flagellar FilamentsNature, 1973