Initiation of 3T3 fibroblast cell division by epidermal growth factor

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Abstract
Epidermal Growth Factor (EGF) at concentrations of 10−9 to 10−10 M initiates cell division in both confluent and low density non-dividing 3T3 cells. Four days after addition of EGF to confluent or low density non-dividing 3T3 cells there is a 2- and 5-fold increase, respectively, in cell number.

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